Cette page rassemble les 290 références scientifiques sur lesquelles s’appuie le Traité scientifique d’aromathérapie clinique. Chaque référence renvoie à la publication d’origine par son DOI ou sa notice PubMed, afin que chacun puisse consulter la source primaire plutôt que son résumé.

Note de lecture. La nature des travaux varie : essais cliniques randomisés, revues systématiques, méta-analyses, mais aussi études in vitro et modèles animaux. Le niveau de preuve est précisé dans chaque fiche, jamais gommé. Une activité observée en laboratoire ne vaut pas démonstration d’efficacité chez l’humain.

Sommaire

Système nerveux (64 références)

  1. López V, Nielsen B, Solas M, Ramírez MJ, Jäger AK. Exploring Pharmacological Mechanisms of Lavender (Lavandula angustifolia) Essential Oil on Central Nervous System Targets. Front Pharmacol. 2017 May 19;8:280.;. DOI : 10.3389/fphar.2017.00280
  2. Xu Y, Ma L, Liu F, Yao L, Wang W, Yang S, Han T. Lavender essential oil fractions alleviate sleep disorders induced by the combination of anxiety and caffeine in mice. J Ethnopharmacol. 2023 Feb 10;302(Pt A):115868. Epub 2022 Oct 26. DOI : 10.1016/j.jep.2022.115868
  3. Harada H, Kashiwadani H, Kanmura Y, Kuwaki T. Linalool Odor-Induced Anxiolytic Effects in Mice. Front Behav Neurosci. 2018 Oct 23;12:241.;. DOI : 10.3389/fnbeh.2018.00241
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  5. Satou T, Kamagata M, Nakashima S, Mori K, Yoshinari M. Effets du linalol inhalé sur le système nerveux autonome chez la souris éveillée. Natural Product Communications. 2024;19(2). DOI : 10.1177/1934578X241232273
  6. Koulivand PH, Khaleghi Ghadiri M, Gorji A. Lavender and the nervous system. Evid Based Complement Alternat Med. 2013;2013:681304. Epub 2013 Mar 14.;. DOI : 10.1155/2013/681304
  7. Chen L, Liu Y, Xu D, Zhang N, Chen Y, Yang J, Sun L. Bêta-myrcène comme composant sédatif-hypnotique de l’huile essentielle de lavande chez des souris atteintes d’insomnie induite par la DL-4-chlorophénylalanine. Pharmaceuticals 2024, 17, 1161. DOI : 10.3390/ph17091161
  8. Piccialli I, Tedeschi V, Caputo L, Amato G, De Martino L, De Feo V, Secondo A, Pannaccione A. L’activité antioxydante du limonène neutralise la neurotoxicité déclenchée par les oligomères Aβ 1-42 dans les neurones corticaux primaires. Antioxydants 2021, 10, 937. DOI : 10.3390/antiox10060937
  9. Cao B, Ni HY, Li J, Zhou Y, Bian XL, Tao Y, Cai CY, Qin C, Wu HY, Chang L, Luo CX, Zhu DY. (+)-Borneol suppresses conditioned fear recall and anxiety-like behaviors in mice. Biochem Biophys Res Commun. 2018 Jan 8;495(2):1588-1593. Epub 2017 Dec 6. DOI : 10.1016/j.bbrc.2017.12.025
  10. Zhang QL, Fu BM, Zhang ZJ. Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood-brain barrier permeability. Drug Deliv. 2017 Nov;24(1):1037-1044.;. DOI : 10.1080/10717544.2017.1346002
  11. Lindsey LP, Daphney CM, Oppong-Damoah A, Uchakin PN, Abney SE, Uchakina ON, Khusial RD, Akil A, Murnane KS. The cannabinoid receptor 2 agonist, β-caryophyllene, improves working memory and reduces circulating levels of specific proinflammatory cytokines in aged male mice. Behav Brain Res. 2019 Oct 17;372:112012. Epub 2019 Jun 4.;. DOI : 10.1016/j.bbr.2019.112012
  12. Brand-Rubalcava PA, Tejeda-Martínez AR, González-Reynoso O, Nápoles-Medina AY, Chaparro-Huerta V, Flores-Soto ME. β-Caryophyllene decreases neuroinflammation and exerts neuroprotection of dopaminergic neurons in a model of hemiparkinsonism through inhibition of the NLRP3 inflammasome. Parkinsonism Relat Disord. 2023 Dec;117:105906. Epub 2023 Oct 28. DOI : 10.1016/j.parkreldis.2023.105906
  13. Yang M, Lv Y, Tian X, Lou J, An R, Zhang Q, Li M, Xu L, Dong Z. Neuroprotective Effect of β-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation: In Vivo and in Vitro. Front Neurosci. 2017 Oct 26;11:583.;. DOI : 10.3389/fnins.2017.00583
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  15. Stojanović NM, Ranđelović PJ, Simonović M, Radić M, Todorović S, Corrigan M, Harkin A, Boylan F. Constituants des huiles essentielles comme agents anti-inflammatoires et neuroprotecteurs : un aperçu de la modulation de la microglie. Int. J. Mol. Sci. 2024, 25, 5168. DOI : 10.3390/ijms25105168
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  17. Khan A, Vaibhav K, Javed H, Tabassum R, Ahmed ME, Khan MM, Khan MB, Shrivastava P, Islam F, Siddiqui MS, Safhi MM, Islam F. 1,8-cineole (eucalyptol) mitigates inflammation in amyloid Beta toxicated PC12 cells: relevance to Alzheimer’s disease. Neurochem Res. 2014 Feb;39(2):344-52. Epub 2013 Dec 31. DOI : 10.1007/s11064-013-1231-9
  18. Tan L, Liao FF, Long LZ, Ma XC, Peng YX, Lu JM, Qu H, Fu CG. Essential oils for treating anxiety: a systematic review of randomized controlled trials and network meta-analysis. Front Public Health. 2023 Jun 1;11:1144404.;. DOI : 10.3389/fpubh.2023.1144404
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  20. Karimzadeh Z, Azizzadeh Forouzi M, Rahiminezhad E, Ahmadinejad M, Dehghan M. The Effects of Lavender and Citrus aurantium on Anxiety and Agitation of the Conscious Patients in Intensive Care Units: A Parallel Randomized Placebo-Controlled Trial. Biomed Res Int. 2021 Jun 15;2021:5565956.;. DOI : 10.1155/2021/5565956
  21. Ebrahimi H, Mardani A, Basirinezhad MH, Hamidzadeh A, Eskandari F. The effects of Lavender and Chamomile essential oil inhalation aromatherapy on depression, anxiety and stress in older community-dwelling people: A randomized controlled trial. Explore (NY). 2022 May-Jun;18(3):272-278. Epub 2021 Jan 9. DOI : 10.1016/j.explore.2020.12.012
  22. Soleimani M, Kashfi LS, Mirmohamadkhani M, Ghods AA. The effect of aromatherapy with peppermint essential oil on anxiety of cardiac patients in emergency department: A placebo-controlled study. Complement Ther Clin Pract. 2022 Feb;46:101533. Epub 2022 Jan 5. https://pubmed.ncbi.nlm.nih.gov/35007899/. DOI : 10.1016/j.ctcp.2022.101533
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  30. Sánchez-Vidaña DI, Po KK, Fung TK, Chow JK, Lau WK, So PK, Lau BW, Tsang HW. Lavender essential oil ameliorates depression-like behavior and increases neurogenesis and dendritic complexity in rats. Neurosci Lett. 2019 May 14;701:180-192. Epub 2019 Feb 28. DOI : 10.1016/j.neulet.2019.02.042
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  40. Pandur E, Major B, Rák T, Sipos K, Csutak A, Horváth G. Linalool and Geraniol Defend Neurons from Oxidative Stress, Inflammation, and Iron Accumulation in In Vitro Parkinson’s Models. Antioxidants (Basel). 2024 Jul 29;13(8):917.;. DOI : 10.3390/antiox13080917
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  42. Hu Y, Zhao Y, Mao Z, Yang J, Huang B, Miao J, Miao M. Inhalation of Acori Tatarinowii Rhizoma essential oil alleviates dyskinesia in Parkinson’s disease rats through the regulation of neuroinflammation. J Ethnopharmacol. 2025 May 28;348:119705. Epub 2025 Apr 15. DOI : 10.1016/j.jep.2025.119705
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